HEARTWORMS IN CATS
Heartworms are 9-11” long worms that live in a cat’s heart or in the arteries leading to the lungs known as pulmonary
arteries. Although heartworms occur commonly in dogs, most people do not consider them a problem for the cat.
However, recent studies of cats with heart and respiratory diseases have found an incidence of heartworms that is far
greater than previously thought.
How are heartworms transmitted to a cat?
Heartworms are transmitted by mosquitoes. When an infected mosquito bites a cat, it deposits baby
heartworms (larvae). The larvae migrate and mature for several months, ending up in the right side of
the heart and the pulmonary arteries. They mature into adult heartworms about six months from the time
they enter the cat. Shortly thereafter, they begin to release immature heartworms, known as microfilaria.
Microfilariae live in the cat’s blood for about one month. They are ingested by mosquitoes feeding on
the cat. However, most mosquitoes acquire microfilaria by feeding on heartworm-infected dogs.
Because of their life cycle, it is necessary for a cat to be bitten by a mosquito to be infected with
heartworms. Heartworms are not transmitted directly from one cat to another or from a dog directly to a cat.
How are heartworms diagnosed?
There are several methods used in diagnosing heartworms;
unfortunately, none are 100% reliable so a combination of tests
is often needed. The diagnostic sequence usually progresses
as follows:
Clinical Signs
One of the difficult things about diagnosing heartworms is that
there are no consistent clinical signs. The most common signs are
coughing and rapid breathing. However, both can be caused by
several other diseases. Other common clinical signs include
weight loss and vomiting, also common in other diseases. Some
cats seem to be normal, then die suddenly. This happens due to
a reaction within the lungs to the young heartworms or when
dead or live heartworms enter the pulmonary arteries and
obstruct the flow of blood to the lungs.
Blood Tests
1. There are two relatively new tests that are proving to be very helpful in diagnosing heartworms. The heartworm antibody test determines
that the cat’s immune system has been exposed to heartworms. A positive test may indicate that an active infection is present. However,
cats who have had heartworms but whose heartworms have died will also have antibodies for an unknown period of time. We currently
believe that the antibodies persist for 2-4 months after the heartworms have died. Cats with late stage larvae that are not yet adults and
cats with adult heartworms in places other than the heart may also test positive with the antibody test. This test is very sensitive, so it is
used first. However, if it is positive the next test is performed.
2. The next test is the heartworm antigen test. This detects the presence of adult female heartworms. It is very specific, but not as
sensitive. A positive test indicates that heartworms are present, but a negative test does not mean that they are absent. Because the cat
must have at least two adult female worms present to make this test positive, a negative test may mean that the cat may only have a small
number of worms or that all the worms present are male.
In summary, a diagnosis of heartworms is confirmed if both the antibody and antigen tests are positive. It should be noted that most
veterinarians are able to perform an in-hospital test to detect heartworm antigen in dogs. However, the canine heartworm antigen test is
not as sensitive as the test for cats so using it will result in more false negative results.
3. Blood can be tested for the presence of microfilariae. However, less than 10% of cats with heartworms have microfilariae in their blood,
and microfilariae are only present for 1-4 weeks. Therefore, a negative test means little.
4. Cats suspected of heartworms can be tested for their level of eosinophils. Eosinophils are a type of white blood cells that occur in
increased numbers when certain parasites are present. They are elevated in the presence of heartworms, but this elevation only occurs for
a few months. In addition, cats with intestinal parasites (“worms”) and allergies also commonly have increased eosinophil counts.
Radiographs
Radiographs (x-rays) permit us to view the size and shape of the heart. They also allow us to measure the diameter of the pulmonary
arteries. Many cats with heartworms have an increase in the size of the pulmonary arteries; they may suddenly come to an apparent stop
(blunted) on their way to the lungs due to worms obstructing them. However, many cats with heartworms have no abnormal findings on their
radiographs, especially early in the infection.
An angiogram is an x-ray study in which contrast material (dye) is injected into the heart or veins and is seen as it goes through the
pulmonary arteries. This illuminates the arteries so they can be better seen. There is some risk with this procedure so it is not used often.
Ultrasound
An ultrasound machine produces an image of internal organs and structures without the use of radiation. It is a testing procedure that is
becoming more and more common in veterinary practices. With it, one is able to view the internal structures of the heart and the pulmonary
arteries. In some cats, the actual heartworms can be seen; this finding confirms the presence of heartworms. However, in many cats the
worms are not seen.
Can heartworms be treated?
There is no drug approved for treating heartworms in cats. One of the drugs for treating dogs has been used in cats, but there are potential
side-effects. Another problem is that when the heartworms die they pass through the pulmonary arteries to the lungs. This can result in
sudden death. Thus, we have a dilemma when a cat is diagnosed with heartworms. One of two choices must be made:
1. Treat with the drug designed for dogs. However, this is a drug that has been shown to have side-effects in cats. These side-effects
include acute pulmonary (lung) failure and death in a small percentage of cats.
2. Treat the symptoms of heartworm disease and hope the cat outlives the worms. Since heartworms live in a cat for about two years,
several months of treatment are needed. When cats are in a crisis, they are treated with oxygen and corticosteroids (“cortisone”) to relieve
the reaction occurring in the pulmonary arteries and lungs, and, if needed, drugs to remove fluid from the lungs (diuretics). When they are
stable, they are treated continuously or periodically with corticosteroids. However, the threat of an acute crisis or sudden death always
exists.
Is there a way to prevent heartworms?
It is strongly recommended that all dogs receive year-round monthly heartworm preventative. It is well accepted that even dogs in very cold
climates should be on heartworm prevention at least part of the year. There are excellent feline heartworm preventatives now available.
Prevention of heartworm disease in cats is safe and easy. The reasons that heartworm prevention should be considered for your cat are:
1. Diagnostic Difficulty. Diagnosing heartworms is not as easy in cats as in dogs. A simple and reliable in-hospital blood test is not yet
available, and the tests that are most reliable must be sent to an outside laboratory. Often, radiographs or ultrasound studies are needed
to confirm the diagnosis. Many cats are diagnosed with an autopsy following sudden death.
2. Unknown Incidence. Heartworms are not nearly as common in cats as they are in dogs. However, they are probably more common than
we realize. As we look more aggressively for heartworms in cats with better and better tests, we expect to find that the incidence is greater
than previously thought.
3. No Good Treatment. There is no good treatment for heartworm-infected cats. Effective drugs are not available, and cats that seem to
be doing well may die suddenly. Treating heartworm infections in cats is risky, and not treating these cats is just as risky. If they are cured
of the disease, it takes about two years.
4. Prevention Is Easy. Cats given heartworm prevention drugs have not shown signs of toxicity. There is a wide margin of safety, even in
kittens as young as six weeks of age.
5. Indoor Cats Get Heartworms, Too. Exposure to mosquitoes is required for transmission. Cats do not have to be exposed to cats or
dogs infected with heartworms. Obviously, cats that go outdoors are more likely to be exposed; however, about 25% of cats that are
diagnosed with heartworms are reported by their owners to be indoor only. This simply means that mosquitoes that come into the house
are just as dangerous as the ones outdoors.
Heartworms are 9-11” long worms that live in a cat’s heart or in the arteries leading to the lungs known as pulmonary
arteries. Although heartworms occur commonly in dogs, most people do not consider them a problem for the cat.
However, recent studies of cats with heart and respiratory diseases have found an incidence of heartworms that is far
greater than previously thought.
How are heartworms transmitted to a cat?
Heartworms are transmitted by mosquitoes. When an infected mosquito bites a cat, it deposits baby
heartworms (larvae). The larvae migrate and mature for several months, ending up in the right side of
the heart and the pulmonary arteries. They mature into adult heartworms about six months from the time
they enter the cat. Shortly thereafter, they begin to release immature heartworms, known as microfilaria.
Microfilariae live in the cat’s blood for about one month. They are ingested by mosquitoes feeding on
the cat. However, most mosquitoes acquire microfilaria by feeding on heartworm-infected dogs.
Because of their life cycle, it is necessary for a cat to be bitten by a mosquito to be infected with
heartworms. Heartworms are not transmitted directly from one cat to another or from a dog directly to a cat.
How are heartworms diagnosed?
There are several methods used in diagnosing heartworms;
unfortunately, none are 100% reliable so a combination of tests
is often needed. The diagnostic sequence usually progresses
as follows:
Clinical Signs
One of the difficult things about diagnosing heartworms is that
there are no consistent clinical signs. The most common signs are
coughing and rapid breathing. However, both can be caused by
several other diseases. Other common clinical signs include
weight loss and vomiting, also common in other diseases. Some
cats seem to be normal, then die suddenly. This happens due to
a reaction within the lungs to the young heartworms or when
dead or live heartworms enter the pulmonary arteries and
obstruct the flow of blood to the lungs.
Blood Tests
1. There are two relatively new tests that are proving to be very helpful in diagnosing heartworms. The heartworm antibody test determines
that the cat’s immune system has been exposed to heartworms. A positive test may indicate that an active infection is present. However,
cats who have had heartworms but whose heartworms have died will also have antibodies for an unknown period of time. We currently
believe that the antibodies persist for 2-4 months after the heartworms have died. Cats with late stage larvae that are not yet adults and
cats with adult heartworms in places other than the heart may also test positive with the antibody test. This test is very sensitive, so it is
used first. However, if it is positive the next test is performed.
2. The next test is the heartworm antigen test. This detects the presence of adult female heartworms. It is very specific, but not as
sensitive. A positive test indicates that heartworms are present, but a negative test does not mean that they are absent. Because the cat
must have at least two adult female worms present to make this test positive, a negative test may mean that the cat may only have a small
number of worms or that all the worms present are male.
In summary, a diagnosis of heartworms is confirmed if both the antibody and antigen tests are positive. It should be noted that most
veterinarians are able to perform an in-hospital test to detect heartworm antigen in dogs. However, the canine heartworm antigen test is
not as sensitive as the test for cats so using it will result in more false negative results.
3. Blood can be tested for the presence of microfilariae. However, less than 10% of cats with heartworms have microfilariae in their blood,
and microfilariae are only present for 1-4 weeks. Therefore, a negative test means little.
4. Cats suspected of heartworms can be tested for their level of eosinophils. Eosinophils are a type of white blood cells that occur in
increased numbers when certain parasites are present. They are elevated in the presence of heartworms, but this elevation only occurs for
a few months. In addition, cats with intestinal parasites (“worms”) and allergies also commonly have increased eosinophil counts.
Radiographs
Radiographs (x-rays) permit us to view the size and shape of the heart. They also allow us to measure the diameter of the pulmonary
arteries. Many cats with heartworms have an increase in the size of the pulmonary arteries; they may suddenly come to an apparent stop
(blunted) on their way to the lungs due to worms obstructing them. However, many cats with heartworms have no abnormal findings on their
radiographs, especially early in the infection.
An angiogram is an x-ray study in which contrast material (dye) is injected into the heart or veins and is seen as it goes through the
pulmonary arteries. This illuminates the arteries so they can be better seen. There is some risk with this procedure so it is not used often.
Ultrasound
An ultrasound machine produces an image of internal organs and structures without the use of radiation. It is a testing procedure that is
becoming more and more common in veterinary practices. With it, one is able to view the internal structures of the heart and the pulmonary
arteries. In some cats, the actual heartworms can be seen; this finding confirms the presence of heartworms. However, in many cats the
worms are not seen.
Can heartworms be treated?
There is no drug approved for treating heartworms in cats. One of the drugs for treating dogs has been used in cats, but there are potential
side-effects. Another problem is that when the heartworms die they pass through the pulmonary arteries to the lungs. This can result in
sudden death. Thus, we have a dilemma when a cat is diagnosed with heartworms. One of two choices must be made:
1. Treat with the drug designed for dogs. However, this is a drug that has been shown to have side-effects in cats. These side-effects
include acute pulmonary (lung) failure and death in a small percentage of cats.
2. Treat the symptoms of heartworm disease and hope the cat outlives the worms. Since heartworms live in a cat for about two years,
several months of treatment are needed. When cats are in a crisis, they are treated with oxygen and corticosteroids (“cortisone”) to relieve
the reaction occurring in the pulmonary arteries and lungs, and, if needed, drugs to remove fluid from the lungs (diuretics). When they are
stable, they are treated continuously or periodically with corticosteroids. However, the threat of an acute crisis or sudden death always
exists.
Is there a way to prevent heartworms?
It is strongly recommended that all dogs receive year-round monthly heartworm preventative. It is well accepted that even dogs in very cold
climates should be on heartworm prevention at least part of the year. There are excellent feline heartworm preventatives now available.
Prevention of heartworm disease in cats is safe and easy. The reasons that heartworm prevention should be considered for your cat are:
1. Diagnostic Difficulty. Diagnosing heartworms is not as easy in cats as in dogs. A simple and reliable in-hospital blood test is not yet
available, and the tests that are most reliable must be sent to an outside laboratory. Often, radiographs or ultrasound studies are needed
to confirm the diagnosis. Many cats are diagnosed with an autopsy following sudden death.
2. Unknown Incidence. Heartworms are not nearly as common in cats as they are in dogs. However, they are probably more common than
we realize. As we look more aggressively for heartworms in cats with better and better tests, we expect to find that the incidence is greater
than previously thought.
3. No Good Treatment. There is no good treatment for heartworm-infected cats. Effective drugs are not available, and cats that seem to
be doing well may die suddenly. Treating heartworm infections in cats is risky, and not treating these cats is just as risky. If they are cured
of the disease, it takes about two years.
4. Prevention Is Easy. Cats given heartworm prevention drugs have not shown signs of toxicity. There is a wide margin of safety, even in
kittens as young as six weeks of age.
5. Indoor Cats Get Heartworms, Too. Exposure to mosquitoes is required for transmission. Cats do not have to be exposed to cats or
dogs infected with heartworms. Obviously, cats that go outdoors are more likely to be exposed; however, about 25% of cats that are
diagnosed with heartworms are reported by their owners to be indoor only. This simply means that mosquitoes that come into the house
are just as dangerous as the ones outdoors.
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Animal Hospital of Fate 1001 North W.E.Crawford (Highway 66 in Fate) Rockwall, Texas 75087 |
1001 North W.E.Crawford (Highway 66 in Fate) Rockwall, Texas 75087 972-722-0066 |
| Dusty B. Goucher, DVM |
